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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 2 | ||
| Ligand | BDBM50029973 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1438384 (CHEMBL3383059) | ||
| Ki | 2.2±n/a nM | ||
| Citation |  Lucchesi, V; Hurst, DP; Shore, DM; Bertini, S; Ehrmann, BM; Allarà, M; Lawrence, L; Ligresti, A; Minutolo, F; Saccomanni, G; Sharir, H; Macchia, M; Di Marzo, V; Abood, ME; Reggio, PH; Manera, C CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides. J Med Chem57:8777-91 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 2 | |||
| Name: | Cannabinoid receptor 2 | ||
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 39690.94 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34972 | ||
| Residue: | 360 | ||
| Sequence: |
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| BDBM50029973 | |||
| n/a | |||
| Name | BDBM50029973 | ||
| Synonyms: | CHEMBL3353447 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H27F2N3O2 | ||
| Mol. Mass. | 487.5404 | ||
| SMILES | CC1CCC(CC1)NC(=O)c1cc2cc(cnc2n(Cc2ccc(F)cc2)c1=O)-c1ccc(F)cc1 |(18.76,-2.03,;17.43,-2.8,;17.43,-4.34,;16.11,-5.11,;14.76,-4.34,;14.75,-2.81,;16.09,-2.04,;13.43,-5.12,;12.1,-4.36,;12.09,-2.82,;10.77,-5.14,;9.43,-4.38,;8.11,-5.15,;6.77,-4.39,;5.44,-5.16,;5.44,-6.7,;6.77,-7.47,;8.11,-6.69,;9.44,-7.46,;9.45,-9,;10.78,-9.77,;10.78,-11.3,;12.11,-12.07,;13.44,-11.3,;14.78,-12.06,;13.44,-9.75,;12.1,-8.99,;10.78,-6.69,;12.11,-7.45,;4.1,-4.39,;4.1,-2.84,;2.76,-2.07,;1.42,-2.85,;.09,-2.08,;1.43,-4.4,;2.77,-5.16,)| | ||
| Structure | 
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