| Reaction Details |
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 | Report a problem with these data |
| Target | Bifunctional chorismate mutase/prephenate dehydratase |
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| Ligand | BDBM50030313 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1431488 (CHEMBL3389853) |
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| IC50 | 85000±n/a nM |
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| Citation |  Meneely, KM; Luo, Q; Riley, AP; Taylor, B; Roy, A; Stein, RL; Prisinzano, TE; Lamb, AL Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism. Bioorg Med Chem22:5961-9 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bifunctional chorismate mutase/prephenate dehydratase |
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| Name: | Bifunctional chorismate mutase/prephenate dehydratase |
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| Synonyms: | CM | CMPDT_ECOLI | Chorismate mutase | JW2580 | P-protein | PDT | Prephenate dehydratase | pheA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43112.35 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_109500 |
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| Residue: | 386 |
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| Sequence: | MTSENPLLALREKISALDEKLLALLAERRELAVEVGKAKLLSHRPVRDIDRERDLLERLI
TLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNKINPHSARIAFLGPKGSYSHLAA
RQYAARHFEQFIESGCAKFADIFNQVETGQADYAVVPIENTSSGAINDVYDLLQHTSLSI
VGEMTLTIDHCLLVSGTTDLSTINTVYSHPQPFQQCSKFLNRYPHWKIEYTESTSAAMEK
VAQAKSPHVAALGSEAGGTLYGLQVLERIEANQRQNFTRFVVLARKAINVSDQVPAKTTL
LMATGQQAGALVEALLVLRNHNLIMTRLESRPIHGNPWEEMFYLDIQANLESAEMQKALK
ELGEITRSMKVLGCYPSENVVPVDPT
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| BDBM50030313 |
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| n/a |
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| Name | BDBM50030313 |
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| Synonyms: | CHEMBL3343828 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H9N3O7S |
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| Mol. Mass. | 387.324 |
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| SMILES | Oc1c(\C=C2\SC(=O)N(C2=O)c2ccccc2)cc(cc1[N+]([O-])=O)[N+]([O-])=O |
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| Structure | 
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