| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tubulin beta chain |
|---|
| Ligand | BDBM50030766 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1437750 (CHEMBL3383000) |
|---|
| Kd | 1300±n/a nM |
|---|
| Citation |  Hayashi, Y; Takeno, H; Chinen, T; Muguruma, K; Okuyama, K; Taguchi, A; Takayama, K; Yakushiji, F; Miura, M; Usui, T; Hayashi, Y Development of a new benzophenone-diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure. ACS Med Chem Lett5:1094-8 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tubulin beta chain |
|---|
| Name: | Tubulin beta chain |
|---|
| Synonyms: | Beta-tubulin | TBB_PIG | Tubulin beta chain |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49840.26 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | ChEMBL_105107 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYV
PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM
AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATADEQGEFEEEGEEDEA
|
|
|
|---|
| BDBM50030766 |
|---|
| n/a |
|---|
| Name | BDBM50030766 |
|---|
| Synonyms: | CHEMBL3342339 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H17N3O3 |
|---|
| Mol. Mass. | 395.4101 |
|---|
| SMILES | O=C(c1ccccc1)c1cccc(\C=c2/[nH]c(=O)\c(=C\c3ccccn3)[nH]c2=O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
