| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
|---|
| Ligand | BDBM50031490 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1438565 (CHEMBL3386096) |
|---|
| EC50 | 0.530000±n/a nM |
|---|
| Citation |  Testa, C; Scrima, M; Grimaldi, M; D'Ursi, AM; Dirain, ML; Lubin-Germain, N; Singh, A; Haskell-Luevano, C; Chorev, M; Rovero, P; Papini, AM 1,4-disubstituted-[1,2,3]triazolyl-containing analogues of MT-II: design, synthesis, conformational analysis, and biological activity. J Med Chem57:9424-34 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocyte-stimulating hormone receptor |
|---|
| Name: | Melanocyte-stimulating hormone receptor |
|---|
| Synonyms: | MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 35238.60 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1498846 |
|---|
| Residue: | 315 |
|---|
| Sequence: | MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIA
ITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDV
LICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITY
YKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAAT
LTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRS
QELRMTLKEVLLCSW
|
|
|
|---|
| BDBM50031490 |
|---|
| n/a |
|---|
| Name | BDBM50031490 |
|---|
| Synonyms: | CHEMBL3358540 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C51H73N17O8 |
|---|
| Mol. Mass. | 1052.2344 |
|---|
| SMILES | CCCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CN=[N+]=[N-])NC(=O)[C@H](CCCC)NC(C)=O)C(N)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
