| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
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| Ligand | BDBM50031494 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1438565 (CHEMBL3386096) |
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| EC50 | 0.240000±n/a nM |
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| Citation |  Testa, C; Scrima, M; Grimaldi, M; D'Ursi, AM; Dirain, ML; Lubin-Germain, N; Singh, A; Haskell-Luevano, C; Chorev, M; Rovero, P; Papini, AM 1,4-disubstituted-[1,2,3]triazolyl-containing analogues of MT-II: design, synthesis, conformational analysis, and biological activity. J Med Chem57:9424-34 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocyte-stimulating hormone receptor |
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| Name: | Melanocyte-stimulating hormone receptor |
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| Synonyms: | MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35238.60 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1498846 |
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| Residue: | 315 |
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| Sequence: | MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIA
ITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDV
LICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITY
YKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAAT
LTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRS
QELRMTLKEVLLCSW
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| BDBM50031494 |
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| n/a |
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| Name | BDBM50031494 |
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| Synonyms: | CHEMBL3358537 |
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| Type | Small organic molecule |
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| Emp. Form. | C51H69N17O8 |
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| Mol. Mass. | 1048.2027 |
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| SMILES | CCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN=[N+]=[N-])C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC#C)C(N)=O |r| |
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| Structure | 
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