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TargetCarbonic anhydrase 1
LigandBDBM50031587
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1440922
Kd>200000±n/a nM
Citation Dudutiene VMatuliene JSmirnov ATimm DDZubriene ABaranauskiene LMorkunaite VSmirnoviene JMichailoviene VJuozapaitiene VMickeviciute AKazokaite JBak?yte SKasiliauskaite AJachno JRevuckiene JKi?onaite MPilipuityte VIvanauskaite EMilinaviciute GSmirnovas VPetrikaite VKairys VPetrauskas VNorvai?as PLinge DGibie?a PCapkauskaite EZak?auskas AKazlauskas EManakova EGra?ulis SLadbury JEMatulis D Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX. J Med Chem 57:9435-46 (2014) [PubMed]  Article
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Carbonic anhydrase 1
Name:Carbonic anhydrase
Synonyms:CA-I | CAB | Carbonate dehydratase I | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA
Type:Enzyme
Mol. Mass.:28873.37
Organism:Homo sapiens (Human)
Description:P00915
Residue:261
Sequence:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
PMQHNNRPTQPLKGRTVRASF
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BDBM50031587
n/a
NameBDBM50031587
Synonyms:CHEMBL3359180
TypeSmall organic molecule
Emp. Form.C26H35F3N2O2S2
Mol. Mass.528.694
SMILESNS(=O)(=O)c1c(F)c(F)c(SCCc2ccccc2)c(F)c1NC1CCCCCCCCCCC1
Structure
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