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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Carbonic anhydrase 1 | ||
| Ligand | BDBM50429899 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1441654 | ||
| Kd | <50±n/a nM | ||
| Citation |  Dudutiene V; Matuliene J; Smirnov A; Timm DD; Zubriene A; Baranauskiene L; Morkunaite V; Smirnoviene J; Michailoviene V; Juozapaitiene V; Mickeviciute A; Kazokaite J; Bak?yte S; Kasiliauskaite A; Jachno J; Revuckiene J; Ki?onaite M; Pilipuityte V; Ivanauskaite E; Milinaviciute G; Smirnovas V; Petrikaite V; Kairys V; Petrauskas V; Norvai?as P; Linge D; Gibie?a P; Capkauskaite E; Zak?auskas A; Kazlauskas E; Manakova E; Gra?ulis S; Ladbury JE; Matulis D Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX. J Med Chem 57:9435-46 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Carbonic anhydrase 1 | |||
| Name: | Carbonic anhydrase | ||
| Synonyms: | CA-I | CAB | Carbonate dehydratase I | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 28873.37 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P00915 | ||
| Residue: | 261 | ||
| Sequence: |
| ||
| BDBM50429899 | |||
| n/a | |||
| Name | BDBM50429899 | ||
| Synonyms: | CHEMBL2333416 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C8H7F4NO3S2 | ||
| Mol. Mass. | 305.27 | ||
| SMILES | NS(=O)(=O)c1c(F)c(F)c(SCCO)c(F)c1F | ||
| Structure | 
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