| Reaction Details |
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 | Report a problem with these data |
| Target | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 |
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| Ligand | BDBM50031827 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1437893 (CHEMBL3384857) |
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| Ki | 68100±n/a nM |
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| Citation |  Chang, L; Lee, SY; Leonczak, P; Rozenski, J; De Jonghe, S; Hanck, T; Müller, CE; Herdewijn, P Imidazopyridine- and purine-thioacetamide derivatives: potent inhibitors of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1). J Med Chem57:10080-100 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 |
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| Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 |
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| Synonyms: | Alkaline phosphodiesterase I | CD_antigen=CD203c | E-NPP 3 | ENPP3 | ENPP3_HUMAN | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 | NPPase | Nucleotide pyrophosphatase | PD-Ibeta | PDNP3 | Phosphodiesterase I beta | Phosphodiesterase I/nucleotide pyrophosphatase 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 100124.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_101240 |
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| Residue: | 875 |
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| Sequence: | MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFD
ASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCL
QRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTL
MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLS
SKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERIS
TLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRN
LHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNS
EEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGG
GNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLN
HLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEI
TATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPT
VPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEE
FRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHY
FVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVR
DVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI
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| BDBM50031827 |
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| n/a |
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| Name | BDBM50031827 |
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| Synonyms: | CHEMBL3360884 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18N4O4S |
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| Mol. Mass. | 374.414 |
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| SMILES | COc1ccc2nc(SCC(=O)Nc3ccc(OC)c(OC)c3)[nH]c2n1 |
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| Structure | 
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