| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 11 |
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| Ligand | BDBM50032272 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1440130 (CHEMBL3382543) |
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| Ki | 1000±n/a nM |
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| Citation |  Maolanon, AR; Villadsen, JS; Christensen, NJ; Hoeck, C; Friis, T; Harris, P; Gotfredsen, CH; Fristrup, P; Olsen, CA Methyl effect in azumamides provides insight into histone deacetylase inhibition by macrocycles. J Med Chem57:9644-57 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 11 |
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| Name: | Histone deacetylase 11 |
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| Synonyms: | HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11 |
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| Type: | Chromatin regulator; hydrolase; repressor |
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| Mol. Mass.: | 39187.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96DB2 |
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| Residue: | 347 |
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| Sequence: | MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
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| BDBM50032272 |
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| n/a |
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| Name | BDBM50032272 |
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| Synonyms: | CHEMBL3352994 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H38N4O7 |
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| Mol. Mass. | 518.6025 |
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| SMILES | CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| |
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| Structure | 
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