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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50037706
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1438832 (CHEMBL3390300)
Ki 14±n/a nM
Citation Gawaskar, SSchepmann, DBonifazi, AWünsch, B Synthesis, GluN2B affinity and selectivity of benzo[7]annulen-7-amines. Bioorg Med Chem22:6638-46 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:Protein
Mol. Mass.:25307.17
Organism:Cavia porcellus (Guinea pig)
Description:Q60492
Residue:223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50037706
n/a
NameBDBM50037706
Synonyms:CHEMBL3357791
TypeSmall organic molecule
Emp. Form.C23H29N
Mol. Mass.319.4831
SMILESC1C[C@H](CC[C@H]1NC1CCc2ccccc2CC1)c1ccccc1 |r,wU:5.6,2.20,(12.23,-10.22,;13,-11.55,;12.25,-12.88,;10.71,-12.89,;9.94,-11.57,;10.7,-10.23,;9.92,-8.91,;8.37,-8.93,;7.72,-10.34,;6.2,-10.7,;4.96,-9.73,;3.62,-10.52,;2.28,-9.74,;2.28,-8.19,;3.62,-7.42,;4.95,-8.18,;6.17,-7.2,;7.69,-7.53,;13.01,-14.21,;12.25,-15.54,;13.02,-16.86,;14.55,-16.85,;15.32,-15.51,;14.54,-14.2,)|
Structure
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