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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50037704
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1438832
Ki 182±n/a nM
Citation Gawaskar SSchepmann DBonifazi AWŁnsch B Synthesis, GluN2B affinity and selectivity of benzo[7]annulen-7-amines. Bioorg Med Chem 22:6638-46 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma-1 receptor
Synonyms:OPRS1 | SIGMAR1 | Sigma 1-type opioid receptor | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:Protein
Mol. Mass.:25307.17
Organism:Cavia porcellus (Guinea pig)
Description:Q60492
Residue:223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50037704
n/a
NameBDBM50037704
Synonyms:CHEMBL3357789
TypeSmall organic molecule
Emp. Form.C21H26N2
Mol. Mass.306.4445
SMILESC1CN(CCN1C1CCc2ccccc2CC1)c1ccccc1
Structure
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