| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Ligand | BDBM50039668 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1446026 (CHEMBL3379139) |
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| IC50 | 3680±n/a nM |
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| Citation |  Li, X; Li, L; Zhou, Q; Zhang, N; Zhang, S; Zhao, R; Liu, D; Jing, Y; Zhao, L Synthesis of the novel elemonic acid derivatives as Pin1 inhibitors. Bioorg Med Chem Lett24:5612-5 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18248.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502595 |
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| Residue: | 163 |
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| Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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| BDBM50039668 |
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| n/a |
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| Name | BDBM50039668 |
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| Synonyms: | CHEMBL3357846 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H46O5 |
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| Mol. Mass. | 534.726 |
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| SMILES | [H][C@]1(CC[C@]2(C)C3=C(CC[C@@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@]1([H])CC3)[C@H](CCC(O)=O)C(=O)OCc1ccccc1 |r,c:6| |
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| Structure | 
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