| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 3 |
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| Ligand | BDBM50041088 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1445730 (CHEMBL3374867) |
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| Ki | 390±n/a nM |
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| Citation |  Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Rodent selectivity of piperidine-4-yl-1H-indoles, a series of CC chemokine receptor-3 (CCR3) antagonists: insights from a receptor model. Bioorg Med Chem Lett25:229-35 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 3 |
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| Name: | C-C chemokine receptor type 3 |
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| Synonyms: | CCR3_RAT | Ccr3 | Cmkbr3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41648.91 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1445730 |
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| Residue: | 359 |
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| Sequence: | MASNEEELKTVVETFETTPYEYEWAPPCEKVSIRELGSWLLPPLYSLVFIVGLLGNMMVV
LILIKYRKLQIMTNIYLLNLAISDLLFLFTVPFWIHYVLWNEWGFGHCMCKMLSGLYYLA
LYSEIFFIILLTIDRYLAIVHAVLALRARTVTFATITSIITWGFAVLAALPEFIFHESQD
NFGDLSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHK
AIQLIFVVMIVFFIFWTPYNLVLLLSAFHSTFLETSCQQSIHLDLAMQVTEVITHTHCCI
NPIIYAFVGERFRKHLRLFFHRNVAIYLRKYISFLPGEKLERTSSVSPSTGEQEISVVF
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| BDBM50041088 |
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| n/a |
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| Name | BDBM50041088 |
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| Synonyms: | CHEMBL3355962 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H31F2N3O2S |
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| Mol. Mass. | 535.648 |
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| SMILES | CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1cc(ccn1)C(O)=O |
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| Structure | 
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