| Reaction Details |
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 | Report a problem with these data |
| Target | Probable C-C chemokine receptor type 3 |
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| Ligand | BDBM50041184 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1445729 (CHEMBL3374866) |
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| Ki | 92±n/a nM |
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| Citation |  Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Rodent selectivity of piperidine-4-yl-1H-indoles, a series of CC chemokine receptor-3 (CCR3) antagonists: insights from a receptor model. Bioorg Med Chem Lett25:229-35 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Probable C-C chemokine receptor type 3 |
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| Name: | Probable C-C chemokine receptor type 3 |
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| Synonyms: | C-C CKR-3 | C-C chemokine receptor type 3 | CC-CKR-3 | CCR-3 | CCR3_MOUSE | CD_antigen=CD193 | CKR3 | Ccr3 | Cmkbr1l2 | Cmkbr3 | MIP-1 alpha RL2 | Macrophage inflammatory protein 1-alpha receptor-like 2 | Probable C-C chemokine receptor type 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41791.57 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1445729 |
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| Residue: | 359 |
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| Sequence: | MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVV
LILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLA
LYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQD
SFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHK
AIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCI
NPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF
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| BDBM50041184 |
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| n/a |
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| Name | BDBM50041184 |
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| Synonyms: | CHEMBL3355943 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27FN2OS |
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| Mol. Mass. | 398.537 |
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| SMILES | OCc1[nH]c2ccccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 |
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| Structure | 
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