Reaction Details | |||
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Target | Neurotensin receptor type 1 | ||
Ligand | BDBM50041427 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1446256 (CHEMBL3373066) | ||
Ki | >25±n/a nM | ||
Citation | Thomas, JB; Giddings, AM; Olepu, S; Wiethe, RW; Harris, DL; Narayanan, S; Warner, KR; Sarret, P; Longpre, JM; Runyon, SP; Gilmour, BP Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2. Bioorg Med Chem Lett25:292-6 (2014) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Neurotensin receptor type 1 | |||
Name: | Neurotensin receptor type 1 | ||
Synonyms: | NTR1_RAT | Neurotensin receptor 1 | Ntsr | Ntsr1 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 47070.64 | ||
Organism: | Rattus norvegicus | ||
Description: | ChEMBL_1466612 | ||
Residue: | 424 | ||
Sequence: |
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BDBM50041427 | |||
n/a | |||
Name | BDBM50041427 | ||
Synonyms: | CHEMBL3356853 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H24ClN3O5 | ||
Mol. Mass. | 469.917 | ||
SMILES | COc1cccc(OC)c1-c1nc(nc2ccc(Cl)cc12)C(=O)NC1(CCCCC1)C(O)=O |(41.35,-22.47,;42.69,-23.24,;42.69,-24.79,;41.36,-25.56,;41.36,-27.11,;42.7,-27.88,;44.04,-27.1,;45.37,-27.87,;45.38,-29.42,;44.03,-25.55,;45.36,-24.78,;46.7,-25.55,;48.03,-24.77,;48.03,-23.23,;46.67,-22.47,;46.66,-20.94,;45.33,-20.18,;44.01,-20.96,;42.66,-20.21,;44.02,-22.47,;45.35,-23.24,;49.37,-25.54,;49.38,-27.08,;50.71,-24.76,;52.04,-25.53,;53.38,-26.3,;54.7,-25.53,;54.71,-23.99,;53.38,-23.22,;52.04,-23.99,;52.05,-27.08,;50.72,-27.85,;53.39,-27.84,)| | ||
Structure |