| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50042597 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1444456 (CHEMBL3373564) |
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| EC50 | 390±n/a nM |
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| Citation |  Riether, D; Zindell, R; Wu, L; Betageri, R; Jenkins, JE; Khor, S; Berry, AK; Hickey, ER; Ermann, M; Albrecht, C; Ceci, A; Gemkow, MJ; Nagaraja, NV; Romig, H; Sauer, A; Thomson, DS Selective CB2 receptor agonists. Part 2: Structure-activity relationship studies and optimization of proline-based compounds. Bioorg Med Chem Lett25:581-6 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50042597 |
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| n/a |
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| Name | BDBM50042597 |
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| Synonyms: | CHEMBL3353890 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H26N4O5S |
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| Mol. Mass. | 398.477 |
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| SMILES | CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C(=O)N2CCS(=O)(=O)CC2)no1 |r| |
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| Structure | 
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