Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cathepsin K | ||
| Ligand | BDBM50042856 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1444643 | ||
| IC50 | 19000±n/a nM | ||
| Citation |  Grosche P; Sirockin F; Mac Sweeney A; Ramage P; Erbel P; Melkko S; Bernardi A; Hughes N; Ellis D; Combrink KD; Jarousse N; Altmann E Structure-based design and optimization of potent inhibitors of the adenoviral protease. Bioorg Med Chem Lett 25:438-43 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cathepsin K | |||
| Name: | Cathepsin K | ||
| Synonyms: | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 36975.68 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P43235 | ||
| Residue: | 329 | ||
| Sequence: |
| ||
| BDBM50042856 | |||
| n/a | |||
| Name | BDBM50042856 | ||
| Synonyms: | CHEMBL3354495 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H27Cl2N5O3 | ||
| Mol. Mass. | 540.441 | ||
| SMILES | CN(C)CCOc1ccc(cc1C(=O)C(C)(C)c1cc(Cl)cc(Cl)c1)C(=O)NCc1ccnc(n1)C#N | ||
| Structure | 
| ||