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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine/threonine-protein kinase Sgk1 | ||
| Ligand | BDBM50043017 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1444807 (CHEMBL3379050) | ||
| IC50 | <1.5±n/a nM | ||
| Citation |  Rosse, G Novel azaindazole sulfonamides inhibitors of serum and glucocorticoid regulated kinase. ACS Med Chem Lett6:19-20 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine/threonine-protein kinase Sgk1 | |||
| Name: | Serine/threonine-protein kinase Sgk1 | ||
| Synonyms: | SGK | SGK1 | SGK1_HUMAN | Serine/threonine-protein kinase Sgk1 | Serine/threonine-protein kinase Sgk1 (SGK) | Serum/glucocorticoid regulated kinase | Serum/glucocorticoid-regulated kinase 1 (SGK1) | ||
| Type: | Other Protein Type | ||
| Mol. Mass.: | 48954.40 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Recombinant human SGK-1 enzyme produced in a baculovirus system. | ||
| Residue: | 431 | ||
| Sequence: |
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| BDBM50043017 | |||
| n/a | |||
| Name | BDBM50043017 | ||
| Synonyms: | CHEMBL3355027 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H21ClN6O4S | ||
| Mol. Mass. | 524.979 | ||
| SMILES | OC1CCC(CC1)Oc1nc(nc2[nH]ncc12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2C#N)cc1 |(68.02,-2.5,;66.48,-2.49,;65.7,-3.83,;64.16,-3.83,;63.39,-2.48,;64.16,-1.15,;65.7,-1.16,;61.85,-2.48,;61.08,-3.82,;59.54,-3.83,;58.77,-5.16,;59.54,-6.5,;61.08,-6.49,;62.1,-7.64,;63.51,-7.03,;63.36,-5.5,;61.86,-5.17,;57.23,-5.15,;56.46,-6.49,;54.91,-6.48,;54.15,-5.14,;52.61,-5.13,;51.84,-6.46,;53.17,-7.23,;51.83,-8,;50.29,-6.47,;49.52,-5.14,;47.98,-5.14,;47.2,-3.81,;47.22,-6.47,;47.99,-7.8,;49.53,-7.8,;50.3,-9.14,;51.07,-10.47,;54.92,-3.81,;56.46,-3.81,)| | ||
| Structure | 
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