Ki Summary

Reaction Details

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Target

Trypsin

Ligand

BDBM50286441

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_1450738 (CHEMBL3363613)

IC50

>200±n/a nM

Citation

Liu, L; Jokela, J; Wahlsten, M; Nowruzi, B; Permi, P; Zhang, YZ; Xhaard, H; Fewer, DP; Sivonen, K Nostosins, Trypsin Inhibitors Isolated from the Terrestrial Cyanobacterium Nostoc sp. Strain FSN. J Nat Prod77:1784-90 (2014) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Trypsin

Name:

Trypsin

Synonyms:

TRYP_PIG

Type:

PROTEIN

Mol. Mass.:

24411.24

Organism:

Sus scrofa

Description:

ChEMBL_1450738

Residue:

231

Sequence:

FPTDDDDKIVGGYTCAANSIPYQVSLNSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGE
HNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAA
GTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDS
CQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN

BDBM50286441

n/a

Name

BDBM50286441

Synonyms:

(S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylamino)-4-methyl-pentanoic acid (1-formyl-4-guanidino-butyl)-amide | (S)-2-Acetylamino-4-methyl-pentanoic acid [(R)-1-((S)-1-formyl-4-guanidino-butylcarbamoyl)-3-methyl-butyl]-amide | (S)-2-Acetylamino-4-methyl-pentanoic acid [(S)-1-((S)-1-formyl-4-guanidino-butylcarbamoyl)-3-methyl-butyl]-amide | (S)-2-[(S)-2-((S)-2-Acetylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-5-guanidino-pentanoic acid | (S)-2-acetylamino-4-methyl-pentanoic acid [(S)-2-(1-formyl-4-guanidino-butylamino)-4-methyl-pentanoyl]-amide | 2-Acetylamino-4-methyl-pentanoic acid [1-(1-formyl-4-guanidino-butylcarbamoyl)-3-methyl-butyl]-amide | Ac-LLR-CHO | Ac-Leu-Leu-Arg-H | CHEMBL129157

Type

Small organic molecule

Emp. Form.

C20H38N6O5

Mol. Mass.

442.5529

SMILES

CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

Structure