| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase FKBP1B |
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| Ligand | BDBM50030448 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1458980 (CHEMBL3369573) |
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| Kd | 0.400000±n/a nM |
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| Citation |  Gibbs, AC Elements and modulation of functional dynamics. J Med Chem57:7819-37 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase FKBP1B |
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| Name: | Peptidyl-prolyl cis-trans isomerase FKBP1B |
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| Synonyms: | 12.6 kDa FKBP | FK506-binding protein 1B | FKB1B_HUMAN | FKBP-12.6 | FKBP-1B | FKBP12.6 | FKBP1B | FKBP1L | FKBP9 | Immunophilin FKBP12.6 | OTK4 | PPIase FKBP1B | Peptidyl-prolyl cis-trans isomerase FKBP1B | Rotamase | h-FKBP-12 | mTOR/FKBP12A/FKBP12B |
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| Type: | PROTEIN |
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| Mol. Mass.: | 11785.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1458980 |
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| Residue: | 108 |
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| Sequence: | MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF
EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE
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| BDBM50030448 |
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| n/a |
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| Name | BDBM50030448 |
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| Synonyms: | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | CHEMBL269732 | TACROLIMUS |
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| Type | Small organic molecule |
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| Emp. Form. | C44H69NO12 |
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| Mol. Mass. | 804.0182 |
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| SMILES | CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC |r,t:45| |
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| Structure | 
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