| Reaction Details |
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 | Report a problem with these data |
| Target | KiSS-1 receptor |
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| Ligand | BDBM50045511 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1448383 (CHEMBL3376867) |
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| EC50 | 4.1±n/a nM |
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| Citation |  Asami, T; Nishizawa, N; Matsui, H; Takatsu, Y; Suzuki, A; Kiba, A; Terada, M; Nishibori, K; Nakayama, M; Ban, J; Matsumoto, S; Tarui, N; Ikeda, Y; Yamaguchi, M; Kusaka, M; Ohtaki, T; Kitada, C Physicochemically and pharmacokinetically stable nonapeptide KISS1 receptor agonists with highly potent testosterone-suppressive activity. J Med Chem57:6105-15 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| KiSS-1 receptor |
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| Name: | KiSS-1 receptor |
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| Synonyms: | Gpr54 | KISSR_RAT | Kiss1r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42915.37 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1448383 |
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| Residue: | 396 |
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| Sequence: | MAAEATLGPNVSWWAPSNASGCPGCGVNASDGPGSAPRPLDAWLVPLFFAALMLLGLVGN
SLVIFVICRHKHMQTVTNFYIANLAATDVTFLLCCVPFTALLYPLPTWVLGDFMCKFVNY
IQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALTVSLSIWVGSAAVSAPVLAL
HRLSPGPHTYCSEAFPSRALERAFALYNLLALYLLPLLATCACYGAMLRHLGRAAVRPAP
TDGALQGQLLAQRAGAVRTKVSRLVAAVVLLFAACWGPIQLFLVLQALGPSGAWHPRSYA
AYALKIWAHCMSYSNSALNPLLYAFLGSHFRQAFCRVCPCGPQRQRRPHASAHSDRAAPH
SVPHSRAAHPVRVRTPEPGNPVRRSPSVQDEHTAPL
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| BDBM50045511 |
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| n/a |
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| Name | BDBM50045511 |
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| Synonyms: | CHEMBL3314228 |
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| Type | Small organic molecule |
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| Emp. Form. | C61H81N17O13 |
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| Mol. Mass. | 1260.4019 |
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| SMILES | CNC(=N)NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc1ccncc1)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| |
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| Structure | 
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