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TargetKiSS-1 receptor
LigandBDBM50045513
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1448386
Ki 0.088000±n/a nM
Citation Asami TNishizawa NMatsui HTakatsu YSuzuki AKiba ATerada MNishibori KNakayama MBan JMatsumoto STarui NIkeda YYamaguchi MKusaka MOhtaki TKitada C Physicochemically and pharmacokinetically stable nonapeptide KISS1 receptor agonists with highly potent testosterone-suppressive activity. J Med Chem 57:6105-15 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
KiSS-1 receptor
Name:KiSS-1 receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:42915.37
Organism:Rattus norvegicus
Description:ChEMBL_1448383
Residue:396
Sequence:
MAAEATLGPNVSWWAPSNASGCPGCGVNASDGPGSAPRPLDAWLVPLFFAALMLLGLVGN
SLVIFVICRHKHMQTVTNFYIANLAATDVTFLLCCVPFTALLYPLPTWVLGDFMCKFVNY
IQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALTVSLSIWVGSAAVSAPVLAL
HRLSPGPHTYCSEAFPSRALERAFALYNLLALYLLPLLATCACYGAMLRHLGRAAVRPAP
TDGALQGQLLAQRAGAVRTKVSRLVAAVVLLFAACWGPIQLFLVLQALGPSGAWHPRSYA
AYALKIWAHCMSYSNSALNPLLYAFLGSHFRQAFCRVCPCGPQRQRRPHASAHSDRAAPH
SVPHSRAAHPVRVRTPEPGNPVRRSPSVQDEHTAPL
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  Blast E-value cutoff:
BDBM50045513
n/a
NameBDBM50045513
Synonyms:KISSPEPTIN-10 | Kisspeptin-10
TypeSmall organic molecule
Emp. Form.C63H83N17O14
Mol. Mass.1302.4386
SMILESCC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Structure
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