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TargetPotassium voltage-gated channel subfamily E member 1
LigandBDBM50045830
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1456351 (CHEMBL3368360)
IC50>33000±n/a nM
Citation Georgsson, JBergström, FNordqvist, AWatson, MJBlundell, CDJohansson, MJPetersson, AUYuan, ZQZhou, YKristensson, LKakol-Palm, DTyrchan, CWellner, EBauer, UBrodin, PSvensson Henriksson, A GPR103 antagonists demonstrating anorexigenic activity in vivo: design and development of pyrrolo[2,3-c]pyridines that mimic the C-terminal Arg-Phe motif of QRFP26. J Med Chem57:5935-48 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Potassium voltage-gated channel subfamily E member 1
Name:Potassium voltage-gated channel subfamily E member 1
Synonyms:Delayed rectifier potassium channel subunit IsK | IKs producing slow voltage-gated potassium channel subunit beta Mink | KCNE1 | KCNE1_HUMAN | KCNQ1(Kv7.1)/KCNE1(MinK) | Minimal potassium channel | Voltage-gated potassium channel beta subunit Mink | Voltage-gated potassium channel, IKs
Type:PROTEIN
Mol. Mass.:14676.11
Organism:Homo sapiens (Human)
Description:ChEMBL_1456351
Residue:129
Sequence:
MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG
IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT
HLPETKPSP
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  Blast E-value cutoff:
BDBM50045830
n/a
NameBDBM50045830
Synonyms:CHEMBL3314362
TypeSmall organic molecule
Emp. Form.C23H26ClN3O
Mol. Mass.395.925
SMILESCN(C)Cc1cc2CCN(Cc2cc1C)C(=O)c1cc2cc(Cl)ccc2n1C
Structure
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