| Reaction Details |
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 | Report a problem with these data |
| Target | Ectonucleoside triphosphate diphosphohydrolase 2 |
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| Ligand | BDBM50048062 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1453714 (CHEMBL3364116) |
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| IC50 | 40000±n/a nM |
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| Citation |  Gillerman, I; Lecka, J; Simhaev, L; Munkonda, MN; Fausther, M; Martín-Satué, M; Senderowitz, H; Sévigny, J; Fischer, B 2-Hexylthio-ß,¿-CH2-ATP is an effective and selective NTPDase2 inhibitor. J Med Chem57:5919-34 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ectonucleoside triphosphate diphosphohydrolase 2 |
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| Name: | Ectonucleoside triphosphate diphosphohydrolase 2 |
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| Synonyms: | CD39L1 | ENTP2_HUMAN | ENTPD2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53675.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1453714 |
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| Residue: | 495 |
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| Sequence: | MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA
DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG
ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF
IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF
LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS
LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG
LPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAF
GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV
LLLRQVHSAKLPSTI
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| BDBM50048062 |
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| n/a |
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| Name | BDBM50048062 |
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| Synonyms: | CHEMBL3314932 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H30N5O12P3S |
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| Mol. Mass. | 621.433 |
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| SMILES | CCCCCCSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]3O)c2n1 |r| |
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| Structure | 
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