| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM50048064 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1453719 (CHEMBL3364121) |
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| IC50 | >100000±n/a nM |
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| Citation |  Hajdu, Z; Nicolussi, S; Rau, M; Lorántfy, L; Forgo, P; Hohmann, J; Csupor, D; Gertsch, J Identification of endocannabinoid system-modulating N-alkylamides from Heliopsis helianthoides var. scabra and Lepidium meyenii. J Nat Prod77:1663-9 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | MAG lipase | MGLL_MOUSE | Mgll | Monoacylglycerol lipase | Monoglyceride Lipase (MGL) |
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| Type: | Hydrolase |
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| Mol. Mass.: | 33391.67 |
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| Organism: | Mus musculus (mouse) |
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| Description: | Assays were using membranes of recombinant MAG Lipase transiently transfected in COS-7 cells. |
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| Residue: | 303 |
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| Sequence: | MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDE
LAHMLKGLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDVLQHVDTIQKDYPDVPIFLLG
HSMGGAISILVAAERPTYFSGMVLISPLVLANPESASTLKVLAAKLLNFVLPNMTLGRID
SSVLSRNKSEVDLYNSDPLVCRAGLKVCFGIQLLNAVARVERAMPRLTLPFLLLQGSADR
LCDSKGAYLLMESSRSQDKTLKMYEGAYHVLHRELPEVTNSVLHEVNSWVSHRIAAAGAG
CPP
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| BDBM50048064 |
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| n/a |
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| Name | BDBM50048064 |
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| Synonyms: | CHEMBL3314942 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H27NO |
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| Mol. Mass. | 297.4345 |
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| SMILES | CC#CC#CC\C=C/CCC\C=C\C=C\C(=O)NCC(C)C |
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| Structure | 
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