| Reaction Details |
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 | Report a problem with these data |
| Target | 40S ribosomal protein S27 |
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| Ligand | BDBM50048364 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1446775 (CHEMBL3381090) |
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| IC50 | >10000±n/a nM |
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| Citation |  Casale, E; Amboldi, N; Brasca, MG; Caronni, D; Colombo, N; Dalvit, C; Felder, ER; Fogliatto, G; Galvani, A; Isacchi, A; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Casuscelli, F Fragment-based hit discovery and structure-based optimization of aminotriazoloquinazolines as novel Hsp90 inhibitors. Bioorg Med Chem22:4135-50 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 40S ribosomal protein S27 |
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| Name: | 40S ribosomal protein S27 |
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| Synonyms: | MPS-1 | MPS1 | Metallopan-stimulin 1 | RPS27 | RS27_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 9472.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1446775 |
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| Residue: | 84 |
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| Sequence: | MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCS
TVLCQPTGGKARLTEGCSFRRKQH
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|
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| BDBM50048364 |
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| n/a |
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| Name | BDBM50048364 |
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| Synonyms: | CHEMBL3309997 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N5O3 |
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| Mol. Mass. | 363.37 |
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| SMILES | OCCCNc1ccc2c3ncnn3c(nc2c1)-c1ccc2OCOc2c1 |
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| Structure | 
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