| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM50324356 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1460062 (CHEMBL3368596) |
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| Ki | 38±n/a nM |
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| Citation |  Chegaev, K; Lazzarato, L; Tamboli, Y; Boschi, D; Blangetti, M; Scozzafava, A; Carta, F; Masini, E; Fruttero, R; Supuran, CT; Gasco, A Furazan and furoxan sulfonamides are stronga-carbonic anhydrase inhibitors and potential antiglaucoma agents. Bioorg Med Chem22:3913-21 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM50324356 |
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| n/a |
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| Name | BDBM50324356 |
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| Synonyms: | 3-phenyl-4-sulfamoyl-1,2,5-oxadiazole 2-oxide | CHEMBL1215508 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H7N3O4S |
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| Mol. Mass. | 241.224 |
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| SMILES | NS(=O)(=O)c1no[n+]([O-])c1-c1ccccc1 |
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| Structure | 
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