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TargetMu-type opioid receptor
LigandBDBM50055061
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1447930
Ki 4300±n/a nM
Citation Bourgeois CWerfel EGalla FLehmkuhl KTorres-Gómez HSchepmann DKögel BChristoph TStraßburger WEnglberger WSoeberdt MHüwel SGalla HJWünsch B Synthesis and pharmacological evaluation of 5-pyrrolidinylquinoxalines as a novel class of peripherally restricted¿-opioid receptor agonists. J Med Chem 57:6845-60 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50055061
n/a
NameBDBM50055061
Synonyms:CHEMBL3323508
TypeSmall organic molecule
Emp. Form.C27H33Cl2N3O2
Mol. Mass.502.476
SMILESOC1CCN(C1)C1CCCC2C1N(CCN2Cc1ccccc1)C(=O)Cc1ccc(Cl)c(Cl)c1
Structure
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