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TargetBeta-2 adrenergic receptor
LigandBDBM50055250
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1449717
IC50 23±n/a nM
Citation Arnold NBeattie DBradley MBrearley ABrown LCharlton SJFairhurst RAFarr DFozard JFullerton JGosling MHatto JJanus DJones DJordan LLewis CMaas JMcCarthy CMercer MOakman HPress NProfit RSchuerch FSykes DTaylor RJTrifilieff ATuffnell A The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting▀2-adrenoceptor agonist. Bioorg Med Chem Lett 24:4341-7 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor
Name:Beta-2 adrenergic receptor
Synonyms:adrenergic Beta2
Type:Enzyme Catalytic Domain
Mol. Mass.:46993.24
Organism:GUINEA PIG
Description:adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4
Residue:418
Sequence:
MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKD
AINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRF
HTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNG
KTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50055250
n/a
NameBDBM50055250
Synonyms:CHEMBL3323653
TypeSmall organic molecule
Emp. Form.C19H26N2O3S
Mol. Mass.362.486
SMILESO[C@@H](CN[C@H]1CCC[C@H]1C1CCCC1)c1ccc(O)c2[nH]c(=O)sc12 |r|
Structure
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