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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Beta-2 adrenergic receptor | ||
| Ligand | BDBM50055250 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1449717 | ||
| IC50 | 23±n/a nM | ||
| Citation |  Arnold N; Beattie D; Bradley M; Brearley A; Brown L; Charlton SJ; Fairhurst RA; Farr D; Fozard J; Fullerton J; Gosling M; Hatto J; Janus D; Jones D; Jordan L; Lewis C; Maas J; McCarthy C; Mercer M; Oakman H; Press N; Profit R; Schuerch F; Sykes D; Taylor RJ; Trifilieff A; Tuffnell A The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-actingß2-adrenoceptor agonist. Bioorg Med Chem Lett 24:4341-7 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Beta-2 adrenergic receptor | |||
| Name: | Beta-2 adrenergic receptor | ||
| Synonyms: | adrenergic Beta2 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 46993.24 | ||
| Organism: | GUINEA PIG | ||
| Description: | adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4 | ||
| Residue: | 418 | ||
| Sequence: |
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| BDBM50055250 | |||
| n/a | |||
| Name | BDBM50055250 | ||
| Synonyms: | CHEMBL3323653 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H26N2O3S | ||
| Mol. Mass. | 362.486 | ||
| SMILES | O[C@@H](CN[C@H]1CCC[C@H]1C1CCCC1)c1ccc(O)c2[nH]c(=O)sc12 |r| | ||
| Structure | 
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