| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50055260 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1449716 (CHEMBL3378139) |
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| Ki | 120±n/a nM |
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| Citation |  Arnold, N; Beattie, D; Bradley, M; Brearley, A; Brown, L; Charlton, SJ; Fairhurst, RA; Farr, D; Fozard, J; Fullerton, J; Gosling, M; Hatto, J; Janus, D; Jones, D; Jordan, L; Lewis, C; Maas, J; McCarthy, C; Mercer, M; Oakman, H; Press, N; Profit, R; Schuerch, F; Sykes, D; Taylor, RJ; Trifilieff, A; Tuffnell, A The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-actingß2-adrenoceptor agonist. Bioorg Med Chem Lett24:4341-7 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50055260 |
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| n/a |
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| Name | BDBM50055260 |
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| Synonyms: | CHEMBL3323658 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26N2O3S |
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| Mol. Mass. | 398.518 |
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| SMILES | O[C@@H](CN[C@@H]1CCC[C@@H]1CCc1ccccc1)c1ccc(O)c2[nH]c(=O)sc12 |r| |
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| Structure | 
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