| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50362867 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1452246 (CHEMBL3366158) |
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| Ki | 2.4±n/a nM |
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| Citation |  Sampson, D; Bricker, B; Zhu, XY; Peprah, K; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Further evaluation of the tropane analogs of haloperidol. Bioorg Med Chem Lett24:4294-7 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41307.65 |
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| Organism: | RAT |
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| Description: | DOPAMINE D4.4 0 RAT::P30729 |
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| Residue: | 387 |
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| Sequence: | MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASER
ILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASI
FNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVC
CLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPV
SDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRK
RGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVN
SALNPIIYTIFNAEFRSVFRKTLRLRC
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| BDBM50362867 |
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| n/a |
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| Name | BDBM50362867 |
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| Synonyms: | CHEMBL1940403 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23ClFNOS |
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| Mol. Mass. | 379.919 |
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| SMILES | OC1(CCN(CCCSc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 |
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| Structure | 
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