| Reaction Details |
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 | Report a problem with these data |
| Target | Dynamin-2 |
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| Ligand | BDBM50055862 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1458574 (CHEMBL3370892) |
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| IC50 | 43700±n/a nM |
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| Citation |  MacGregor, KA; Abdel-Hamid, MK; Odell, LR; Chau, N; Whiting, A; Robinson, PJ; McCluskey, A Development of quinone analogues as dynamin GTPase inhibitors. Eur J Med Chem85:191-206 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dynamin-2 |
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| Name: | Dynamin-2 |
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| Synonyms: | DYN2_RAT | Dnm2 | Dyn2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 98236.76 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1458574 |
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| Residue: | 870 |
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| Sequence: | MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
SGIVTRRPLILQLIFSKTEYAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
DIEGRKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPTLRSKL
QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL
KEPCLKCVDLVIQELISTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID
IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE
YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL
RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV
DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAEQAQRRD
DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQNTSSHSPTPQRRPVSSVHPPGR
PPAVRGPTPGPPLIPMPVGATSSFSAPPIPSRPGPQNVFANNDPFSAPPQIPSRPARIPP
GIPPGVPSRRAPAAPSRPTIIRPAEPSLLD
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| BDBM50055862 |
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| n/a |
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| Name | BDBM50055862 |
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| Synonyms: | CHEMBL3329969 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14N2O4 |
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| Mol. Mass. | 322.3148 |
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| SMILES | Oc1cccc(NC2=CC(=O)C(Nc3cccc(O)c3)=CC2=O)c1 |c:20,t:7| |
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| Structure | 
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