| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-3 |
|---|
| Ligand | BDBM50055958 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1460270 (CHEMBL3370186) |
|---|
| IC50 | 20±n/a nM |
|---|
| Citation |  Suchaud, V; Gavara, L; Giraud, F; Nauton, L; Théry, V; Anizon, F; Moreau, P Synthesis of pyrazolo[4,3-a]phenanthridines, a new scaffold for Pim kinase inhibition. Bioorg Med Chem22:4704-10 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase pim-3 |
|---|
| Name: | Serine/threonine-protein kinase pim-3 |
|---|
| Synonyms: | PIM3 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 (PIM3) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 35888.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q86V86 |
|---|
| Residue: | 326 |
|---|
| Sequence: | MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
PESCDLRLCTLDPDDVASTTSSSESL
|
|
|
|---|
| BDBM50055958 |
|---|
| n/a |
|---|
| Name | BDBM50055958 |
|---|
| Synonyms: | CHEMBL3326555 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H8N4O2 |
|---|
| Mol. Mass. | 264.2389 |
|---|
| SMILES | [O-][N+](=O)c1cc2[nH]ncc2c2c1ncc1ccccc21 |
|---|
| Structure | 
|
|---|
Search and Browse
