| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Ligand | BDBM50056212 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1449741 (CHEMBL3378164) |
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| Ki | 1900±n/a nM |
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| Citation |  Guo, C; Hou, X; Dong, L; Marakovits, J; Greasley, S; Dagostino, E; Ferre, R; Johnson, MC; Humphries, PS; Li, H; Paderes, GD; Piraino, J; Kraynov, E; Murray, BW Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket. Bioorg Med Chem Lett24:4187-91 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18248.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502595 |
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| Residue: | 163 |
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| Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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| BDBM50056212 |
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| n/a |
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| Name | BDBM50056212 |
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| Synonyms: | CHEMBL3322224 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18N2O3 |
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| Mol. Mass. | 358.3899 |
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| SMILES | OC(=O)C(Cc1cc2ccccc2[nH]1)NC(=O)c1ccc2ccccc2c1 |
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| Structure | 
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