| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen phosphorylase, muscle form |
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| Ligand | BDBM50056222 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1449751 (CHEMBL3378174) |
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| Ki | 1000000±n/a nM |
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| Citation |  Parmenopoulou, V; Kantsadi, AL; Tsirkone, VG; Chatzileontiadou, DS; Manta, S; Zographos, SE; Molfeta, C; Archontis, G; Agius, L; Hayes, JM; Leonidas, DD; Komiotis, D Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-ß-d-glucopyranosylamines. Bioorg Med Chem22:4810-25 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen phosphorylase, muscle form |
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| Name: | Glycogen phosphorylase, muscle form |
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| Synonyms: | Glycogen phosphorylase, muscle form | Muscle glycogen phosphorylase | Myophosphorylase | PYGM | PYGM_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 97097.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1449751 |
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| Residue: | 842 |
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| Sequence: | MSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTV
RDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDM
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEA
DDWLRYGNPWEKARPEFTLPVHFYGHVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVN
TMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERM
DWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFP
GDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKF
QNKTNGITPRRWLVLCNPGLAEVIAERIGEDFISDLDQLRKLLSFVDDEAFIRDVAKVKQ
ENKLKFAAYLEREYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKREPNKFFV
PRTVMIGGKAAPGYHMAKMIIRLVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPA
ADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVD
KLDQRGYNAQEYYDRIPELRQVIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYED
YIKCQEKVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDE
AI
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| BDBM50056222 |
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| n/a |
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| Name | BDBM50056222 |
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| Synonyms: | CHEMBL3322298 |
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| Type | Small organic molecule |
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| Emp. Form. | C42H72O36 |
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| Mol. Mass. | 1152.9995 |
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| SMILES | [H][C@]1(O[C@H]2[C@H](O)[C@@H](O)[C@@]([H])(O[C@H]3[C@H](O)[C@@H](O)[C@@]([H])(O[C@H]4[C@H](O)[C@@H](O)[C@@]([H])(O[C@H]5[C@H](O)[C@@H](O)[C@@]([H])(O[C@H]6[C@H](O)[C@@H](O)[C@@]([H])(O[C@H]7[C@H](O)[C@@H](O)C(O)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO)O[C@@H]3CO)O[C@@H]2CO)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| |
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| Structure | 
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