| Reaction Details |
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 | Report a problem with these data |
| Target | Similar to alpha-tubulin isoform 1 |
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| Ligand | BDBM50005480 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1454104 (CHEMBL3362589) |
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| IC50 | 1800±n/a nM |
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| Citation |  Duan, YT; Sang, YL; Makawana, JA; Teraiya, SB; Yao, YF; Tang, DJ; Tao, XX; Zhu, HL Discovery and molecular modeling of novel 1-indolyl acetate--5-nitroimidazole targeting tubulin polymerization as antiproliferative agents. Eur J Med Chem85:341-51 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Similar to alpha-tubulin isoform 1 |
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| Name: | Similar to alpha-tubulin isoform 1 |
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| Synonyms: | Similar to alpha-tubulin isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 10383.05 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_104716 |
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| Residue: | 99 |
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| Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
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| BDBM50005480 |
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| n/a |
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| Name | BDBM50005480 |
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| Synonyms: | (-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetramethoxystilbene | (Z)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | (combretastatin A-4)2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol | (combretastin A-4)2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol | 2-Methoxy-5-[(Z)-2-(3,4,5-trimethox y-phenyl)-vinyl]-phenol | 2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol | 2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol | 2-methoxy-5-(3,4,5-trimethoxystyryl)phenol | 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]phenol | 5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 5-[(S)-2-Hydroxy-2-(3,4,5-trimethoxy-phenyl)-ethyl]-2-methoxy-phenol | CHEMBL67 | Combrestatin A-4 | Combrestatin A4 | Combretastastin A-4 | Combretastatin | Combretastatin-A4 | Combretastin A-4 | Z-Combretastatin A-4 | combretastatin A-4, (CSA4) | combretastin A4 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20O5 |
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| Mol. Mass. | 316.3484 |
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| SMILES | COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O |
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| Structure | 
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