| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphoethanolamine/phosphocholine phosphatase |
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| Ligand | BDBM46667 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1448918 (CHEMBL3375685) |
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| IC50 | 940±n/a nM |
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| Citation |  Bravo, Y; Teriete, P; Dhanya, RP; Dahl, R; Lee, PS; Kiffer-Moreira, T; Ganji, SR; Sergienko, E; Smith, LH; Farquharson, C; Millán, JL; Cosford, ND Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. Bioorg Med Chem Lett24:4308-11 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphoethanolamine/phosphocholine phosphatase |
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| Name: | Phosphoethanolamine/phosphocholine phosphatase |
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| Synonyms: | PHOP1_HUMAN | PHOSPHO1 | phosphatase, orphan 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 29718.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TCT1 |
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| Residue: | 267 |
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| Sequence: | MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLR
ATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVIL
ISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKV
LSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEP
SSFRASVVPWETAADVRLHLQQVLKSC
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| BDBM46667 |
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| n/a |
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| Name | BDBM46667 |
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| Synonyms: | 2-phenyl-1,2-benzothiazol-3-one | 2-phenyl-1,2-benzothiazol-3-one (1) | MLS-0107957.0001 | acs.jmedchem.1c00409_ST.178 | cid_164981 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H9NOS |
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| Mol. Mass. | 227.282 |
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| SMILES | O=c1n(sc2ccccc12)-c1ccccc1 |
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| Structure | 
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