| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM10869 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1456833 (CHEMBL3367566) |
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| Ki | 19±n/a nM |
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| Citation |  Prete, SD; Vullo, D; Osman, SM; Scozzafava, A; AlOthman, Z; Capasso, C; Supuran, CT Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: theß-class (PgiCAb) versus the¿-class (PgiCA) enzymes. Bioorg Med Chem22:4537-43 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM10869 |
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| n/a |
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| Name | BDBM10869 |
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| Synonyms: | 5-imino-4-methyl-4,5-dihydro-1,3,4-thiadiazole-2-sulfonamide | CHEMBL6753 | aromatic/heteroaromatic sulfonamide 14 |
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| Type | Small organic molecule |
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| Emp. Form. | C3H6N4O2S2 |
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| Mol. Mass. | 194.235 |
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| SMILES | Cn1nc(sc1=N)S(N)(=O)=O |
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| Structure | 
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