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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50059787
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1460710 (CHEMBL3396041)
Ki 230±n/a nM
Citation Sozio, PFiorito, JDi Giacomo, VDi Stefano, AMarinelli, LCacciatore, ICataldi, APacella, STurkez, HParenti, CRescifina, AMarrazzo, A Haloperidol metabolite II prodrug: asymmetric synthesis and biological evaluation on rat C6 glioma cells. Eur J Med Chem90:1-9 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:Protein
Mol. Mass.:25307.17
Organism:Cavia porcellus (Guinea pig)
Description:Q60492
Residue:223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50059787
n/a
NameBDBM50059787
Synonyms:CHEMBL3393790
TypeSmall organic molecule
Emp. Form.C31H35ClFNO3
Mol. Mass.524.066
SMILESOC1(CCN(CCC[C@H](OC(=O)CCCc2ccccc2)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 |r|
Structure
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