| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor A |
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| Ligand | BDBM50030814 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1461999 (CHEMBL3396449) |
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| Ki | >10000±n/a nM |
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| Citation |  Wallinder, C; Sköld, C; Botros, M; Guimond, MO; Hallberg, M; Gallo-Payet, N; Karlén, A; Alterman, M Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands. ACS Med Chem Lett6:178-82 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor A |
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| Name: | Type-1 angiotensin II receptor A |
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| Synonyms: | AGTRA_RAT | ANGIOTENSIN AT1 | Agtr1 | Agtr1a | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | At1a | Type-1A angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40910.53 |
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| Organism: | RAT |
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| Description: | ANGIOTENSIN AT1 AGTR1 RAT::P25095 |
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| Residue: | 359 |
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| Sequence: | MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
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| BDBM50030814 |
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| n/a |
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| Name | BDBM50030814 |
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| Synonyms: | CHEMBL2086892 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29N3O4S2 |
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| Mol. Mass. | 475.624 |
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| SMILES | CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1cccc(Cn2ccnc2)c1 |
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| Structure | 
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