Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Cannabinoid receptor 2 | ||
Ligand | BDBM50062499 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1462820 (CHEMBL3399659) | ||
Ki | 90±n/a nM | ||
Citation | Bertini, S; Parkkari, T; Savinainen, JR; Arena, C; Saccomanni, G; Saguto, S; Ligresti, A; Allarà, M; Bruno, A; Marinelli, L; Di Marzo, V; Novellino, E; Manera, C; Macchia, M Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands. Eur J Med Chem90:526-36 (2015) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Cannabinoid receptor 2 | |||
Name: | Cannabinoid receptor 2 | ||
Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 39690.94 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P34972 | ||
Residue: | 360 | ||
Sequence: |
| ||
BDBM50062499 | |||
n/a | |||
Name | BDBM50062499 | ||
Synonyms: | CHEMBL3397449 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H27NO2 | ||
Mol. Mass. | 337.4553 | ||
SMILES | COc1c(C)cc(cc1C(=O)N[C@H]1CC[C@H](C)CC1)-c1ccccc1 |r,wU:15.16,wD:12.12,(-7.74,3.22,;-6.68,3.84,;-5.34,3.08,;-4.01,3.85,;-4.01,5.08,;-2.67,3.08,;-2.67,1.54,;-4,.77,;-5.34,1.54,;-6.67,.76,;-7.74,1.37,;-6.66,-.78,;-7.99,-1.56,;-9.33,-.79,;-10.66,-1.56,;-10.66,-3.1,;-11.72,-3.72,;-9.32,-3.87,;-7.99,-3.1,;-1.33,.77,;,1.54,;1.33,.77,;1.33,-.77,;,-1.54,;-1.33,-.77,)| | ||
Structure |