| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50063012 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1463313 (CHEMBL3399540) |
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| IC50 | 193870±n/a nM |
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| Citation |  Babkov, DA; Valuev-Elliston, VT; Paramonova, MP; Ozerov, AA; Ivanov, AV; Chizhov, AO; Khandazhinskaya, AL; Kochetkov, SN; Balzarini, J; Daelemans, D; Pannecouque, C; Seley-Radtke, KL; Novikov, MS Scaffold hopping: exploration of acetanilide-containing uracil analogues as potential NNRTIs. Bioorg Med Chem23:1069-81 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50063012 |
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| n/a |
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| Name | BDBM50063012 |
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| Synonyms: | CHEMBL3398100 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23N3O3 |
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| Mol. Mass. | 377.4363 |
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| SMILES | Cc1cc(C)cc(Cn2c(=O)ccn(CC(=O)NCc3ccccc3)c2=O)c1 |
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| Structure | 
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