| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Myeloblastin |
|---|
| Ligand | BDBM50063048 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1463425 (CHEMBL3399762) |
|---|
| IC50 | 2050±n/a nM |
|---|
| Citation |  Hwang, TL; Wang, WH; Wang, TY; Yu, HP; Hsieh, PW Synthesis and pharmacological characterization of 2-aminobenzaldehyde oxime analogs as dual inhibitors of neutrophil elastase and proteinase 3. Bioorg Med Chem23:1123-34 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Myeloblastin |
|---|
| Name: | Myeloblastin |
|---|
| Synonyms: | Leukocyte proteinase 3 | MBN | PRTN3 | PRTN3_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 27816.30 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1463425 |
|---|
| Residue: | 256 |
|---|
| Sequence: | MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV
DWIRSTLRRVEAKGRP
|
|
|
|---|
| BDBM50063048 |
|---|
| n/a |
|---|
| Name | BDBM50063048 |
|---|
| Synonyms: | CHEMBL3398147 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H19NO5S |
|---|
| Mol. Mass. | 361.412 |
|---|
| SMILES | CC(C)(C)C(=O)Oc1ccc(cc1)S(=O)(=O)Nc1ccccc1C=O |
|---|
| Structure | 
|
|---|
Search and Browse
