| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin-releasing peptide receptor |
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| Ligand | BDBM50066009 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1464741 (CHEMBL3407092) |
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| Ki | 0.500000±n/a nM |
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| Citation |  Pourghiasian, M; Liu, Z; Pan, J; Zhang, Z; Colpo, N; Lin, KS; Perrin, DM; Bénard, F (18)F-AmBF3-MJ9: a novel radiofluorinated bombesin derivative for prostate cancer imaging. Bioorg Med Chem23:1500-6 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin-releasing peptide receptor |
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| Name: | Gastrin-releasing peptide receptor |
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| Synonyms: | Bombesin 2 | GRP-R | GRP-preferring bombesin receptor | GRPR | GRPR_HUMAN | Gastrin releasing peptide receptor | Gastrin-releasing peptide receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43214.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Bombesin 2 GRPR 0::P30550 |
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| Residue: | 384 |
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| Sequence: | MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNIT
LIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQ
LTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSD
LHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQS
AYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLH
FVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTS
LKSTNPSVATFSLINGNICHERYV
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| BDBM50066009 |
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| n/a |
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| Name | BDBM50066009 |
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| Synonyms: | CHEMBL3401466 |
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| Type | Small organic molecule |
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| Emp. Form. | C70H104BF3N20O13 |
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| Mol. Mass. | 1501.507 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CN1CCC(CC1)NC(=O)Cn1cc(C[N+](C)(C)C[B-](F)(F)F)nn1)C(C)C)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(N)=O |r| |
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| Structure | 
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