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TargetCarbonic anhydrase 7
LigandBDBM50066132
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1465101
Ki 9.9±n/a nM
Citation Carta FDi Cesare Mannelli LPinard MGhelardini CScozzafava AMcKenna RSupuran CT A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. Bioorg Med Chem 23:1828-40 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 7
Name:Carbonic anhydrase
Synonyms:CA-VII | CA7 | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:Enzyme
Mol. Mass.:29664.11
Organism:Homo sapiens (Human)
Description:Human cloned isozyme.
Residue:264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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  Blast E-value cutoff:
BDBM50066132
n/a
NameBDBM50066132
Synonyms:CHEMBL3402960
TypeSmall organic molecule
Emp. Form.C9H11NO3S
Mol. Mass.213.254
SMILESNS(=O)(=O)c1ccc(OCC=C)cc1
Structure
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