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TargetDelta-type opioid receptor
LigandBDBM50066355
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1465625
Ki 69±n/a nM
Citation Yuan YZaidi SAStevens DLScoggins KLMosier PDKellogg GEDewey WLSelley DEZhang Y Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14-dihydroxy-4,5a-epoxy-6a-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands. Bioorg Med Chem 23:1701-15 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Opioid receptor
Synonyms:DOR-1 | Delta-type opioid receptor | K56 | MSL-2 | OPIATE Delta | OPRD1
Type:Enzyme Catalytic Domain
Mol. Mass.:40577.25
Organism:MOUSE
Description:OPIATE Delta OPRD1 MOUSE::P32300
Residue:372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50066355
n/a
NameBDBM50066355
Synonyms:CHEMBL3401557
TypeSmall organic molecule
Emp. Form.C32H35N3O6
Mol. Mass.557.6368
SMILES[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)c1cc2cc(OC)c(OC)cc2cn1)ccc3O |r,TLB:10:9:17:4.5.6|
Structure
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