| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
|---|
| Ligand | BDBM50066953 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1466178 (CHEMBL3404953) |
|---|
| IC50 | 4.0±n/a nM |
|---|
| Citation |  Piao, YL; Ram Song, A; Cho, H Cell-based biological evaluations of 5-(3-bromo-4-phenethoxybenzylidene)thiazolidine-2,4-dione as promising wound healing agent. Bioorg Med Chem23:2098-103 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
|---|
| Name: | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
|---|
| Synonyms: | 15-PGDH | 15-hydroxyprostaglandin dehydrogenase [NAD+] | HPGD | PGDH1 | PGDH_HUMAN | Prostaglandin dehydrogenase 1 (15-PGDH) | SDR36C1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 28974.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P15428 |
|---|
| Residue: | 266 |
|---|
| Sequence: | MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF
IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD
YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA
ICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNG
AIMKITTSKGIHFQDYDTTPFQAKTQ
|
|
|
|---|
| BDBM50066953 |
|---|
| n/a |
|---|
| Name | BDBM50066953 |
|---|
| Synonyms: | CHEMBL3403240 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H14BrNO3S |
|---|
| Mol. Mass. | 404.278 |
|---|
| SMILES | Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OCCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
