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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Carbonic anhydrase 1 | ||
| Ligand | BDBM50067999 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1466431 (CHEMBL3406376) | ||
| Ki | 615±n/a nM | ||
| Citation |  Bozdag, M; Carta, F; Vullo, D; Akdemir, A; Isik, S; Lanzi, C; Scozzafava, A; Masini, E; Supuran, CT Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action. Bioorg Med Chem23:2368-76 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Carbonic anhydrase 1 | |||
| Name: | Carbonic anhydrase 1 | ||
| Synonyms: | CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 28873.37 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P00915 | ||
| Residue: | 261 | ||
| Sequence: |
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| BDBM50067999 | |||
| n/a | |||
| Name | BDBM50067999 | ||
| Synonyms: | CHEMBL3400803 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C8H13N2NaS2 | ||
| Mol. Mass. | 224.322 | ||
| SMILES | [Na+].[S-]C(=S)N[C@@H]1CN2CCC1CC2 |r,wU:5.3,(7.42,-3.05,;-.25,-3.45,;-.23,-2.28,;-1.25,-1.68,;1.05,-1.55,;2.32,-2.3,;2.3,-3.84,;3.64,-4.61,;4.97,-3.83,;4.97,-2.27,;3.64,-1.5,;3.11,-2.61,;4.14,-3.23,)| | ||
| Structure | 
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