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TargetIntestinal-type alkaline phosphatase
LigandBDBM18073
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1464325 (CHEMBL3404592)
IC50 80210±n/a nM
Citation Al-Rashida, M; Ejaz, SA; Ali, S; Shaukat, A; Hamayoun, M; Ahmed, M; Iqbal, J Diarylsulfonamides and their bioisosteres as dual inhibitors of alkaline phosphatase and carbonic anhydrase: Structure activity relationship and molecular modelling studies. Bioorg Med Chem23:2435-44 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Intestinal-type alkaline phosphatase
Name:Intestinal-type alkaline phosphatase
Synonyms:ALPI | Intestinal alkaline phosphatase | Intestinal alkaline phosphatase (IAP) | Intestinal-type alkaline phosphatase (IAP) | PPBI_BOVIN
Type:Protein
Mol. Mass.:57094.82
Organism:Bos taurus (Cattle)
Description:P19111
Residue:533
Sequence:
MQGACVLLLLGLHLQLSLGLVPVEEEDPAFWNRQAAQALDVAKKLQPIQTAAKNVILFLG
DGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLC
GVKGNYRTIGVSAAARYNQCKTTRGNEVTSVMNRAKKAGKSVGVVTTTRVQHASPAGAYA
HTVNRNWYSDADLPADAQMNGCQDIAAQLVNNMDIDVILGGGRKYMFPVGTPDPEYPDDA
SVNGVRKRKQNLVQAWQAKHQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQD
HTKDPTLQEMTEVALRVVSRNPRGFYLFVEGGRIDHGHHDDKAYMALTEAGMFDNAIAKA
NELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYAL
GGGSRPDVNDSTSEDPSYQQQAAVPQASETHGGEDVAVFARGPQAHLVHGVEEETFVAHI
MAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY
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  Blast E-value cutoff:
BDBM18073
n/a
NameBDBM18073
Synonyms:(2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523 | L-[2,3,4,5,6-3H]phenylalanine | L-phenylalanine | Phenylalanine | US11021454, Compound L-phe
TypeAmino Acid
Emp. Form.C9H11NO2
Mol. Mass.165.1891
SMILESN[C@@H](Cc1ccccc1)C(O)=O
Structure
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