Reaction Details | |||
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Target | Neurotensin receptor type 1 | ||
Ligand | BDBM50019423 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1466612 (CHEMBL3407205) | ||
Ki | 3210±n/a nM | ||
Citation | Thomas, JB; Giddings, AM; Olepu, S; Wiethe, RW; Warner, KR; Sarret, P; Longpre, JM; Runyon, SP; Gilmour, BP The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2. Bioorg Med Chem Lett25:2060-4 (2015) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Neurotensin receptor type 1 | |||
Name: | Neurotensin receptor type 1 | ||
Synonyms: | NTR1_RAT | Neurotensin receptor 1 | Ntsr | Ntsr1 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 47070.64 | ||
Organism: | Rattus norvegicus | ||
Description: | ChEMBL_1466612 | ||
Residue: | 424 | ||
Sequence: |
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BDBM50019423 | |||
n/a | |||
Name | BDBM50019423 | ||
Synonyms: | CHEMBL3290105 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H26FN3O5 | ||
Mol. Mass. | 467.4894 | ||
SMILES | COc1cccc(OC)c1-c1cc(nn1-c1ccc(F)cc1)C(=O)NC1(CCCCC1)C(O)=O |(18.77,-17.38,;19.54,-16.04,;21.08,-16.04,;21.85,-17.38,;23.39,-17.38,;24.16,-16.04,;23.39,-14.71,;24.16,-13.38,;25.7,-13.38,;21.85,-14.71,;20.85,-12.98,;21.48,-11.57,;20.33,-10.54,;19,-11.31,;19.32,-12.81,;18.29,-13.96,;18.76,-15.42,;17.73,-16.57,;16.23,-16.25,;15.2,-17.39,;15.75,-14.78,;16.78,-13.64,;20.49,-9.01,;21.9,-8.38,;19.25,-8.1,;19.41,-6.57,;20.9,-7,;21.99,-5.92,;21.62,-4.43,;20.13,-4,;19.04,-5.09,;17.87,-6.68,;17.01,-5.4,;17.2,-8.06,)| | ||
Structure |